Joost Schalkwijk Selected Research

Elafin

5/2011	Type 2 helper T-cell cytokines induce morphologic and molecular characteristics of atopic dermatitis in human skin equivalent.
9/2008	Development and validation of human psoriatic skin equivalents.
2/2005	Phenotypical and functional differences in germinative subpopulations derived from normal and psoriatic epidermis.
2/2003	Transcriptional regulation of the elafin gene in human keratinocytes.
5/2002	Immunohistochemical expression of SKALP/elafin in squamous cell carcinoma of human lung.

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Joost Schalkwijk Research Topics

Disease

32	Psoriasis (Pustulosis Palmaris et Plantaris) 01/2022 - 07/2002
11	Atopic Dermatitis (Atopic Eczema) 01/2022 - 12/2005
8	Ehlers-Danlos Syndrome (Syndrome, Ehlers-Danlos) 10/2020 - 04/2004
8	Neoplasms (Cancer) 05/2020 - 02/2002
8	Inflammation (Inflammations) 01/2020 - 06/2008
6	Infections 01/2022 - 04/2008
4	Skin Diseases (Skin Disease) 01/2017 - 07/2003
4	Melanoma (Melanoma, Malignant) 12/2012 - 03/2004
3	Dysbiosis 01/2022 - 10/2019
3	Malaria 01/2022 - 04/2015
3	Neoplasm Metastasis (Metastasis) 05/2020 - 03/2004
3	Joint Instability (Joint Laxity) 04/2020 - 09/2004
3	Wounds and Injuries (Trauma) 11/2013 - 01/2007
3	Porcine Reproductive and Respiratory Syndrome (PRRS) 09/2012 - 11/2010
2	Alopecia (Baldness) 10/2017 - 10/2010
2	Cicatrix (Scar) 10/2010 - 01/2004
1	Hyperplasia 01/2022
1	Hypertrophy 01/2022
1	Muscle Weakness 10/2020
1	Blepharitis 01/2019
1	Hypotrichosis 01/2019
1	Eczema 01/2019
1	Photophobia (Light Sensitivity) 01/2019
1	Insulin Resistance 03/2016
1	Body Weight (Weight, Body) 03/2016
1	Neointima 01/2016
1	Exanthema (Rash) 07/2015
1	Arthralgia (Joint Pain) 07/2015
1	Disease Progression 10/2014
1	Starvation 08/2014
1	Burns 11/2013
1	Communicable Diseases (Infectious Diseases) 10/2013
1	Contact Dermatitis (Eczema, Contact) 12/2012
1	Ichthyosis (Xeroderma) 11/2012
1	Infectious Skin Diseases 09/2012
1	Immune System Diseases (Immune Disorders) 01/2012
1	Schnitzler Syndrome 12/2011

Drug/Important Bio-Agent (IBA)

17	Proteins (Proteins, Gene)FDA Link 01/2022 - 02/2003
10	CytokinesIBA 01/2022 - 07/2007
10	tenascin XIBA 10/2020 - 04/2004
7	Biological ProductsIBA 01/2022 - 02/2002
6	Biomarkers (Surrogate Marker)IBA 10/2019 - 07/2002
5	Cystatin MIBA 01/2019 - 07/2003
5	HLA-C Antigens (HLA-C)IBA 11/2017 - 11/2010
5	ElafinIBA 05/2011 - 05/2002
4	Pharmaceutical PreparationsIBA 01/2022 - 08/2002
4	Messenger RNA (mRNA)IBA 05/2020 - 12/2005
3	Pattern Recognition ReceptorsIBA 09/2012 - 11/2010
2	Interleukin-4 (Interleukin 4)IBA 01/2022 - 01/2004
2	Interleukin-6 (Interleukin 6)IBA 01/2022 - 09/2008
2	Coal Tar (Estar)IBA 01/2020 - 02/2013
2	Antimicrobial PeptidesIBA 01/2020 - 12/2005
2	Cysteine Proteinase InhibitorsIBA 01/2019 - 05/2004
2	EnzymesIBA 01/2019 - 08/2014
2	Peptide Hydrolases (Proteases)FDA Link 10/2017 - 10/2010
2	ChemokinesIBA 01/2017 - 03/2014
2	pantetheinase (pantetheine hydrolase)IBA 01/2016 - 09/2009
2	Toll-Like Receptors (Toll-Like Receptor)IBA 07/2015 - 11/2010
2	LigandsIBA 07/2015 - 05/2015
2	Interleukin-1beta (Interleukin 1 beta)IBA 07/2015 - 12/2012
2	Coenzyme A (CoA)IBA 04/2015 - 08/2014
2	Glycoproteins (Glycoprotein)IBA 08/2013 - 01/2007
2	Filaggrin ProteinsIBA 02/2013 - 10/2012
2	DNA (Deoxyribonucleic Acid)IBA 12/2012 - 10/2012
2	Protease Inhibitors (Protease Inhibitor)IBA 11/2012 - 10/2010
2	DefensinsIBA 10/2012 - 10/2012
2	HLA-C*06 antigenIBA 05/2011 - 02/2009
2	beta-DefensinsIBA 01/2009 - 01/2008
1	Interleukin-13IBA 01/2022
1	interleukin 20 (IL-20)IBA 01/2022
1	tofacitinibIBA 01/2022
1	dupilumabIBA 01/2022
1	Interleukin-22 (IL-22)IBA 01/2022
1	Antimalarials (Antimalarial Agents)IBA 01/2022
1	MitogensIBA 01/2022
1	Interleukin-17 (Interleukin 17)IBA 01/2022
1	Oncostatin MIBA 01/2022
1	TenascinIBA 04/2020
1	Succimer (Dimercaptosuccinic Acid)FDA Link 04/2020
1	Aryl Hydrocarbon Receptors (Aryl Hydrocarbon Receptor)IBA 01/2020
1	Tryptophan (L-Tryptophan)FDA Link 10/2019
1	Nonsense Codon (Nonsense Mutation)IBA 01/2019
1	pantothenamideIBA 01/2019
1	Chemokine Receptor D6IBA 01/2017
1	Chemokine ReceptorsIBA 01/2017
1	CC ChemokinesIBA 01/2017
1	Imiquimod (Aldara)FDA LinkGeneric 01/2017
1	Glucose (Dextrose)FDA LinkGeneric 03/2016
1	LipidsIBA 03/2016
1	Interleukin-1 (Interleukin 1)IBA 07/2015
1	Interleukin-2 (IL2)IBA 10/2014
1	PPAR alphaIBA 08/2014
1	Anti-Bacterial Agents (Antibiotics)IBA 10/2013
1	InflammasomesIBA 12/2012
1	canakinumab FDA Link 12/2011

Therapy/Procedure

6	Therapeutics 10/2019 - 01/2004
2	Transplantation 01/2016 - 11/2013
1	Oral Administration 03/2016
1	Lasers (Laser) 01/2015
1	Immunomodulation 01/2012